Nephron number varies between individuals and can be
influenced by developmental and environmental factors. Factors such as maternal
nutrition, gestational age at birth, and other environmental influences affect
nephron endowment. Epidemiological studies have found that individuals with
fewer nephrons are more likely to develop certain health conditions later in
life.

Which observation would provide the strongest
evidence supporting the Brenner Hypothesis?

Question

Nephron number varies between individuals and can be
influenced by developmental and environmental factors. Factors such as maternal
nutrition, gestational age at birth, and other environmental influences affect
nephron endowment. Epidemiological studies have found that individuals with
fewer nephrons are more likely to develop certain health conditions later in
life.

Which observation would provide the strongest
evidence supporting the Brenner Hypothesis?

Accepted Answer

Individuals
with low nephron number show higher rates of hypertension in adulthood

Answer

Prematurely
born infants are more likely to develop diabetes later in life

Answer

Poor
nutrition during gestation reduces nephron number at birth

Answer

Low
nephron number is associated with reduced kidney size

Crowdly

Nephron number varies between individuals and can be influenced by developmenta...

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