A hydropathy plot of the amino acid sequence of a membrane protein begins with a region of high negative hydrophathy, followed by three regions of high positive hydropathy, and ends with a region of high negative hydropathy. Each of the regions of high positive hydropathy spans around 25 residues. The first two regions of high positive hydropathy have a short region of negative hydropathy between them. The second two regions of high positive hydropathy have a far longer region of negative hydropathy between them.

Which (terribly sketched by Nathan) schematic below best fits with the description above?