states there is no history of trauma but mentions she had a history of sickle cell disease. On physical

examination, her upper part of the right shin is very painful, red, swollen, and hot. Her temperature

is 39.2C. An X-ray shows focal bony lysis and loss of trabecular architecture in the metaphysis of the

right tibia. Increased activity of which of the following cells is the most likely cause of bone

reabsorption in this patient?