Patient-derived T cells are genetically modified to express a chimeric antigen receptor (CAR). Afterwards, the T cells are expanded and infused back into the patient. This strategy is known as CAR T cell therapy. Please select the correct statement about CAR T cell therapy.

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T cells isolated from the patient (or allogeneic donor) are genetically modified to express MHC, expanded, and infused back into the patient

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CAR T cells must possess inhibitory receptors

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CARs bind to the MHC II molecule of the target cell

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CAR functions as a normal T cell receptor

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Bypass MHC restriction, as tumor cells often downregulate MHC molecules

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Patient-derived T cells are genetically modified to express a chimeric antigen r...

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