Which statement best describes the use of whole-exome sequencing (WES) compared to targeted gene panels?

Question

Answer

Both WES and gene panels sequence the whole genome at the same depth

Answer

WES focuses on the coding regions where most known disease-causing mutations occur, while panels test specific, well-established disease genes

Answer

Gene panels are less cost-effective than WES and take longer to analyze

Answer

WES sequences the entire genome, while panels only cover non-coding regions

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