Which statement concerning the hedgehog signalling pathwayis correct?

Question

Answer

The introduction of the Smoothened mutation SmoM2 in a mouse model is able to induce medulloblastoma and basal cell carcinoma

Answer

Patched is a positive regulator of hedgehog pathway signalling

Answer

The cilia is not required for regulation of the hedgehog signalling pathway

Answer

Smoothened (Smo) is an inhibitor of the Hedgehog signalling pathway

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