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A 63-year-old man comes to the physician for a follow-up evaluation of chronic, ...
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A 63-year-old man comes to the physician for a follow-up evaluation of chronic, retrosternal chest pain. The pain is worse at night and after heavy meals. He has taken medicines to reduce the production of stomach acids for several months without any relief from his symptoms. An upper endoscopy shows changes in the distal esophagus and in the area above the gastro-oesophageal junction. A biopsy of the distal esophagus shows simple columnar epithelium with goblet cells, which does not occur normally here. Which type of epithelium should normally occur here?
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