Studies of lung tissue from patients with SARS-CoV-2
infection have revealed patterns in the host immune response that correlate
with disease severity. In severe COVID-19, dysregulation of certain immune
pathways contributes to lung injury.

Which statement best explains the molecular basis of lung
damage in severe COVID-19 cases?

Question

Studies of lung tissue from patients with SARS-CoV-2
infection have revealed patterns in the host immune response that correlate
with disease severity. In severe COVID-19, dysregulation of certain immune
pathways contributes to lung injury.

Which statement best explains the molecular basis of lung
damage in severe COVID-19 cases?

Answer

Moderate
cases show reduced interferon expression, which protects lung tissue from
damage

Answer

Severe
cases show reduced interferon production, limiting early antiviral defence and
allowing extensive viral replication and tissue injury

Answer

Downregulation
of interferons is a normal cellular response to all viral infections and is not
linked to pathology

Answer

Severe
cases exhibit excessive activation of inflammatory pathways, resulting in
immune-mediated lung damage

Crowdly

Studies of lung tissue from patients with SARS-CoV-2 infection have revealed pa...

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