Why is ibuprofen a competitive inhibitor of COX enzymes?

Question

Answer

Because it binds very tightly and irreversibly to the active site of COX enzymes.

Answer

Because it binds to a regulatory site of COX enzymes, that is distinct from the active site.

Answer

Because it binds to the active site of COX enzymes in a reversible manner and prevents the substrate from binding to the enzyme.

Answer

Because it reacts with an amino acid residue in the active site of COX enzymes and prevents the substrate from binding to the enzymes.

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