CD8⁺ T cells recognise conserved internal influenza proteins
such as NP and M1. Mutations in these regions often reduce viral replication
efficiency. Variants retaining conserved sequences consistently show higher
fitness.

Over long evolutionary timescales, what outcome is most
likely?

Question

CD8⁺ T cells recognise conserved internal influenza proteins
such as NP and M1. Mutations in these regions often reduce viral replication
efficiency. Variants retaining conserved sequences consistently show higher
fitness.

Over long evolutionary timescales, what outcome is most
likely?

Accepted Answer

Conservation
of internal proteins despite surface antigen variation

Answer

Replacement
of T‑cell immunity by antibody‑mediated control

Answer

Equal
mutation rates across internal and surface proteins

Answer

Progressive
loss of T‑cell recognition across all viral proteins

Crowdly

CD8⁺ T cells recognise conserved internal influenza proteins such as NP and M1....

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