The pathophysiological
progression of type 2 diabetes involves the following key sequences:

Question

Accepted Answer

Impaired insulin sensitivity that drives
glucose intolerance, but chronic pancreatic β cell failure causes type 2
diabetes

Answer

Acute failure of the pancreatic β-cells leading
to impaired glycaemic control and hyperglycaemia

Answer

A rapid decline in insulin sensitivity without a compensatory change in insulin secretion leading to glucose intolerance

Answer

A rapid decline in insulin sensitivity, where
increased insulin secretion becomes the key feature of type 2 diabetes

Crowdly