W hich
of the following correctly traces the step-by-step normal insulin signaling
pathway that leads to glucose uptake in skeletal muscle cells?

Question

Accepted Answer

Insulin
binds receptor →
activation of IRS1 →
activation of phosphoinositide 3-kinase (PI3K) → activation of Protein Kinase B (AKT) → translocation of GLUT4 vesicle channels to the
plasma membrane.

Answer

Insulin binds receptor →
JNK activation → PKC activation → GLUT4 translocation.

Answer

Insulin
binds receptor →
APPL1 recruitment →
ACC activation →
passive diffusion of glucose.

Answer

Insulin
binds receptor →
direct passive entry of glucose through lipid bilayers.

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W hich of the following correctly traces the step-by-step normal insulin signali...

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