Early in an immune response, antibodies with relatively low
affinity for antigen can still bind pathogens effectively when produced as IgM.

Which explanation BEST accounts for this
observation?

Question

Early in an immune response, antibodies with relatively low
affinity for antigen can still bind pathogens effectively when produced as IgM.

Which explanation BEST accounts for this
observation?

Answer

IgM
antibodies undergo rapid somatic hypermutation that improves their ability to
multimerise

Answer

Multiple
antigen-binding sites on secreted IgM allow strong overall binding despite weak
individual interactions

Answer

IgM
antibodies are small enough to penetrate tissues more efficiently

Answer

IgM
antibodies are preferentially selected during affinity maturation

Crowdly