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Oscar was diagnosed with infection by the Sesame Street Virus (SSV). SSV is a single-stranded, negative-sense RNA virus (pictured below).
(A) The SSV
virion pictured above has glycoprotein spikes on the surface of the virion
(structure A). What is the function of
this glycoprotein in the viral life cycle?
(B) Viruses
survive by hijacking host cell machinery to express viral proteins. The schematic of the SSV virion shows a
protein, labelled Viral protein X.
Viral protein X is necessary for both viral genome replication and
protein expression. What type of protein
is viral protein X and why is it packaged into the virion?
(C) Explain
how SSV will express proteins such as Structure C shown in the diagram of the
virion.
(D) SSV has
replicated in Oscar’s cells. In the diagram of the SSV virion, what is
structure B and how is it formed?
[1 + 2 + 3 + 2 = 8 marks][max. 300 words]
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