B cells are crucial to mount an immune response effectively; as a result, they are directed to the lymph node where they differentiate into plasmablasts. Plasmablasts then migrate, for instance, to the bone marrow. Several chemokines and their receptors are responsible for guiding B cells. Which of the following is true?

Question

Accepted Answer

Mature, naïve B cells express CCR7, which binds to CCL19 and CCL21 to facilitate their homing to the lymph node

Answer

The migration of mature, naive B cells to the site of infection is driven by TGF-β

Answer

Not B cells; rather, effector T cells migrate to the bone marrow

Answer

Plasmablasts, which are precursors of plasma cells, are only resident in the lung

Answer

Only immature, activated B cells migrate to the lymph node

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B cells are crucial to mount an immune response effectively; as a result, they a...

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