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Which statement/s is/are correct about the extracellular matrix of the connective tissue?
Type I collagen forms the basal lamina of epithelia.
❌
Proteoglycans are very hydrophilic and behave like polyanions.
✅
Glycosaminoglycans are continuously synthesized and simultaneously degraded in the connective tissue.
✅
Glycoproteins are dominated by the protein component, whereas proteoglycans are dominated by the carbohydrate portion of the molecule.
✅
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Hyaluronic acid
can be cleaved by hyaluronidase of invading bacteria, thus facilitating the penetration of microorganisms through tissues.
✅
is strongly hydrophobic (repelled from a water).
❌
is abundant e.g. in vitreous humor, synovial joint fluid or Wharton's jelly.
✅
belongs to the sulphated glycosaminoglycans of the amorphous extracellular matrix.
❌
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Which statement/s is/are correct about connective tissue cells?
Mast cell degranulation is associated with allergic reactions.
✅
Plasma cells have abundant basophilic cytoplasm and their function is phagocytosis.
❌
Dead neutrophils cause suppuration (pus).
✅
Macrophages can fuse together to form giant multinucleated cells.
✅
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Which statement/s is/are correct about the connective tissue cells?
Plasma cells have a basophilic cytoplasm due to the abundant granular endoplasmic reticulum.
✅
Granulocytes, lymphocytes, and monocytes can penetrate the connective tissue through the wall of microvessels by diapedesis.
✅
Macrophages (histiocytes) produce histamine and release it into the environment after IgE binding.
❌
Myofibroblasts have contractile filaments and are used e.g. in the retraction of healing wounds.
✅
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