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MECHANISM OF DISEASES I A001843 2025-2026

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Which of the following statements concerning osmosis is FALSE?
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One patient with decreased von Willebrand factor activity has most likely derangement in which of the following steps in hemostasis?
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Beta-lactamase production is an example of which of the following types of resistance?
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In cellular events of acute inflammation, cells undergo rolling and adhesion before extravasation to interstitial tissue. Then, leukocytes migrate towards the infection site. What is the commonest exogenous agent that mediates this latter process?
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The most relevant side effect of COX2 selective inhibitors is increased risk of cardiovascular and cerebrovascular events (arterial thrombosis). Which of the following is the cause of this dangerous side effect?
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Which of the following are examples of fungal or bacterial opportunistic infections?
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Cancer cells isolated from a carcinoma have a mutation in a gene coding for a small GTPase. This mutation gives rise to increased and uncontrolled proliferation of cells. Which of the following genes is most likely to be mutated in these cells?
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Meningitis is characterized by the acute onset of fever and stiff neck. During the initial 24 h of the course of aseptic meningitis, an affected person’s cerebrospinal fluid is characterized by
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Which of the following statements concerning the alternative complement pathway is true?
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CXCR4 is a chemokine receptor important for the retention of leukocytes in the bone marrow. Which patients could you envisage that will benefit from blocking CXCR4?
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