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DEV2011 - Early human development from cells to tissues - S1 2025

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The process of meiosis has both similarities and differences in males and females. Which of the following is similar in both male and female meiosis?

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What is the female gonadal somatic cell equivalent to the male Sertoli cell?

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What phenotype would a person have if they had an XY karyotype, but a non-functioning SRY gene?

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Which molecular marker indicates specification of the the germline?

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Haematopoiesis occurs in several locations in the embryo, at different stages during development.  

1) Describe when and where haematopoiesis occurs in the body, including the location, the cell types involved, and the time during embryonic/fetal and post-natal development.  (8 marks)

2) To ensure the process of implantation is successful, what key changes occur in the embryo, and in the endometrium?  (5 marks)

3) What is the role of the yolk sac during embryogenesis in humans?  (2 marks)

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Match each blood cell type with its major function(s). 

Can you also name from which lineage each blood cell type arises?  (lymphoid, myeloid, erythroid)? 

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What is the role of the lymphatic system?  Select all options that apply.

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What cells are precursor cell types required in the process of generating a red blood cell?  Select all those that apply.  

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Blood cells are made in different tissues in the embryo and the adult. Match the locations blood cells are produced to the time in development that blood cells are produced in this location.  

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From which germ layer do blood cells derive?

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