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DEV2011 - Early human development from cells to tissues - S1 2025
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Antennapedia is an example of a homeotic transformation in the fruit fly Drosophila. The effect of homeotic mutations is:
Following a mutagenesis screen where male mice were exposed to the chemical mutagen ENU several embryos with different limb defects were identified after 3 generations of mating. How would the genes responsible for the limb phenotypes be identified?
What does it mean when a cell is “determined”?
CRISPR-Cas9 technology can be used to repair a mutated sequence that causes a single amino acid change within a given gene. Which of the following components are required to achieve this ?
You are assessing foetal cells through a karyotype analysis to determine whether the foetus may have Down syndrome. What information does a karyotype analysis provide?
What is the cause of Down syndrome?
There are major types of techniques used in developmental biology. Match the technique to the appropriate definition.
Neural crest cells are:
Neural crest cells are:
Outline the 4 major stages of germline development up to sex determination. State the stage name, one aspect of that stage (eg cellular behaviour, genes involved etc), and what the germ cells are called at each point (hint you will need to provide 2 names at the last stage).