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IMM2011 - Basic immunology: The body's defence system - S1 2025

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Which cell type is often mobilised in large numbers from the bone marrow during infection?

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In class you will count the number of cells in a blood sample.  The formula to calculate the number of cells/ml is:

Image failed to load: Haemocytometer - cell counting formula.

If you had a blood sample and diluted 50 μl of your sample in 150 μl of white cell diluting fluid, and then counted the cells on a haemocytometer, counting:

  • 89 cells in square A
  • 102 cells in square B
  • 97 cells in square C
  • 99 cells in square D

What number of cells/ml do you have in your sample?  Report as a whole number, using standard notation (e.g. 4300 instead of 4.3 × 103).

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In class you will count the number of cells in a blood sample.  The formula to calculate the number of cells/ml is:

Image failed to load: Haemocytometer - cell counting formula.

If you had a blood sample and diluted 20 μl of your sample in 80 μl of white cell diluting fluid, and then counted the cells on a haemocytometer, counting:

  • 89 cells in square A
  • 102 cells in square B
  • 97 cells in square C
  • 99 cells in square D

What number of cells/ml do you have in your sample?  Report as a whole number, using standard notation (e.g. 4300 instead of 4.3 × 103).

View this question

In class you will count the number of cells in a blood sample.  The formula to calculate the number of cells/ml is:

Image failed to load: Haemocytometer - cell counting formula.

If you had a blood sample and diluted 20 μl of your sample in 80 μl of white cell diluting fluid, and then counted the cells on a haemocytometer, counting:

  • 76 cells in square A
  • 70 cells in square B
  • 67 cells in square C
  • 86 cells in square D

What number of cells/ml do you have in your sample?  Report as a whole number, using standard notation (e.g. 4300 instead of 4.3 × 103).

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When looking at a blood smear, which cell is the largest?

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What is another name for white blood cells?

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In Part B of this exercise you will need to make a 1:20 dilution of sheep blood in white cell diluting fluid, to a total of 1 ml.  You need to use 50 μl of sheep blood cells.  How much white cell diluting fluid in μl do you need to use? (You do not need to include units in your answer.)

(Hint: 1 ml is equal to how many μl?)

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Which method below is the correct way to make a blood smear?

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During B cell development, B cells with BCR that interact strongly with self-antigens can undergo receptor editing. This involves:

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A feature of MHC class I molecules is that:
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