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BMS/GNA2042 - Human Genetics - S2 2025

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Cells must be cultured prior to preparing the metaphase spread. This requires the in vitro growth of human cells in a cell culture medium which was mentioned in the lab video. What is the cell culture medium?

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Diagram the expected pairing of these

two chromosomes in an individual heterozygous for the inversion.

Note: Discuss your drawing with your groupmates

and TA to have full clarity on this diagram. Get it checked with your TA for

feedback. 

U

pload of this diagram to Moodle. You will be able to compare with a

model diagram upon receiving feedback.

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Diagram the expected appearance of the chromosomes involved at the pachytene stage of prophase I and at the end of anaphase I of meiosis in this woman. For anaphase I, draw out both alternate and adjacent I segregation, there is no need to include adjacent II segregation. Label your chromosomes and include the spindles if appropriate. 

Use different colours. Consider what will make each of your meiosis diagrams and informative, accurate and clear as possible. (Discuss with your group and TA). 

Attach your diagrams below, note: .HEIC files not accepted.

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The products from which meiotic events are unlikely to lead to viable progeny? 

Hint: look at the next

question to inform your answer.

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