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BMS/GNA2042 - Human Genetics - S2 2025

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Examine the G-banded karyogram of Linda. In the provided patient file pair the atypical chromosomes with the typical versions of chromosomes from which they may have been derived.

Identify the type of chromosomal rearrangement.

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Choose which image accurately illustrates Linda's family pedigree:

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Interspecies hybrids can arise between the red kangaroo and euro. How many chromosomes are present in somatic cells of the hybrid?

Insert a number only (no spaces)

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Would the hybrid in Q4 be completely fertile?

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Meiosis occurs in the

euro and red kangaroo hybrid in Q4. Diagram the expected appearance of the

chromosomes involved at the pachytene stage of prophase I for chromosomes 5 and

6 of the euro and red kangaroo hybrid. 

Label your chromosomes and include the spindles if appropriate. This question will assist you with answering Q6. Attach your diagrams below, note: .HEIC files not accepted.

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From this tree, which species is the closest relative of the red kangaroo (Macrupus rufus)?

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Genetic locus:

According to OMIM database, use standard nomenclature: <chromosome><arm><region><G-band.sub-band> with no spaces. If there is a range of sub-bands, only enter the first sub-band.

Example: a gene located on chromosome 7, p arm, Region 3, Band 1 and sub-band 2= 7p31.2 

Only enter 7p31.2

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Mode of inheritance:

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