Q7. Which vaccine administration route would be most effective for protecting against RhoV infection of the lower respiratory tract?

Q9. What type of T-cell response would you aim to elicit through vaccination, and how would this response be protective against RhoV infection? (2-3 sentences) (2 marks)

A global research consortium has begun efforts to develop a vaccine to protect against RhoV infection. Although the viral genome has not yet been sequenced, RhoV has been successfully cultured in vitro under PC2-containment conditions using a cell-based system.

Q6. Which vaccine design approach would you recommend for the RhoV vaccine? You must select an approach that is feasible based on the information provided above.

Q3. Scientists discover that RhoV produces an early protein, E1, that binds to and inactivates the retinoblastoma (Rb) protein.

a) Describe the normal function of Rb in host cells. (1-2 sentences) (2 marks)

Q2. RhoV infects and replicates within ciliated epithelial cells in the lower respiratory tract. Where within the epithelial cells is RhoV replication most likely to occur?

Q1. Use the Baltimore classification scheme to classify RhoV.

If you obtain the following second-stage test results, what would the causative microorganism (pathogen) be?

If you see this outcome for a carbohydrate fermentation test, what is the result?

When reading results of a haemolysis test, you observe there is no change in the blood agar. This is classified as what type of haemolysis?

What happens to the medium used for the urease test if the cultured microorganism produces urease? Why does this happen?