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Course 10815

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Explain the pathogenesis of pulmonary TB (from

inhalation to granuloma formation).....

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Explain the role of risk factors in

development of invasive candidiasis in this patient 

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Discuss the pharmaceutical and clinical advantages of Isavuconazonium sulfate.

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Compare Fluconazole and Econazole in terms of their chemical structures, and explain how these structural differences influence their antifungal activity and routes of administration.

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Discuss two clinical reasons why removal of the central venous catheter is essential.

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Compare the role of caspofungin with azole antifungals by stating one key therapeutic advantage in ICU patients.

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Explain the mechanism of action of caspofungin.

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How do we manage

treatment interruption in this case? Provide your recommendations? (1 mark)

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What is the recommended duration of therapy in candidemia?

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When can step-down therapy to fluconazole be considered in the management of invasive candidiasis?

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