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Для студентів медичного факультету №1

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A 75-year-old patient was diagnosed with rectal cancer. Into what regional lymph nodes can the

metastases spread in this case?

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In an experiment, despiralization of the DNA molecule was disrupted in an animal cell. What processes will primarily stop in this cell?
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One of the cause of chronic pancreatitis is autolysis of pancreatic parenchyma due to inorganic conversion of trypsinogen into trypsin. How does this process occur in the duodenum under normal condition?
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A 56-year-old woman complains of pain in the small joints of her hands and feet. She has been

experiencing these symptoms for the last 12 years. Examination of her hands detects a subluxation

of the metacarpophalangeal joints with her fingers bent outwards ("walrus flippers"). There are high

molecular weight immune complexes in the patient’s blood. What diagnosis can be made in this case?

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A 30-year-old patient with a femoral fracture was brought to the hospital after a car accident.

The patient presents with sharply reduced blood pressure of 70/40 mm Hg, a weak pulse, and increased

pain response provoked by the slightest touch in the damaged area. What should be administered in

this case to prevent traumatic shock in the patient?

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Pathologies of lipid metabolism include sphingolipidoses that can be characterized by the accumulation of excess phospholipids and sphingolipids, mainly in the nervous tissue. What disease is associated with accumulation of GM2 ganglioside in the body?
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A patient with acute appendicitis has been hospitalized into the surgical department. An appendectomy

under local anesthesia was initially recommended to the patient. However, it was later discovered that

the patient had a history of frequent allergic reactions to medicines. Select from the list the drug

that would be the optimal chioce for infiltration anesthesia in this case.

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A woman, who was undergoing treatment for insomnia, was found unconscious. Her respiration is inhibited,

she is in a collaptoid state and presents with muscle hypotonia and absence of reflexes. Empty medicine

packages were found at the site of the accident. What medicine could have caused such a condition in

the patient?

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A woman poisoned with unknown substance was hospitalised in a toxicological department. What group of

drugs can be administered to decrease absorption and introduction of the poison to her body?

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A 30-year-old patient has dyspnea fits, mostly at night. He has been diagnosed with bronchial asthma.

What type of allergic reaction according to the Gell-Coombs classification is most likely in this case?

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