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Applied Embryology 2026

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Combine a disorder and probable failure of developmental mechanism properly

insufficient amount of amniotic fluid

persistent septum in the uterus cavity

doubled aortic arch

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In contrast to the somatic cell, embryonic genome has several unique features:

it is physiologically polyploid, undergoing to diploidization due to mitotic reduction of blastomeres

67%

it is created in the zygote, after sperm penetreation to the egg, along with the syngamy of maternal and paternal pronuclei

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it is inactive till embryonic genome activation at 8-16-cell stage

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it is predominantly condensed in heterochromatin and, therefore, it is silenced and transcriptionally inactive

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