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General Histology for Dental Medicine

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An 18-year-old female patient

is coming to the emergency office of the Department of Ophthalmology. She is

suffering from significant swelling of the upper eyelid. The eyelid is markedly

swollen, stiff and reddened in one spot. The eyelid is painful and causes

significant tearing of the entire eye. After examination of the eyelid, the

doctor concludes that it is a chalazion (eyelid cyst or Meibomian cyst). It is

an inflammation of the Meibomian gland of the eyelid, which can be seen in the

picture. What type of gland is it with regard to the mechanism of secretion?

View this question

An 18-year-old female patient

is coming to the emergency office of the Department of Ophthalmology. She is

suffering from significant swelling of the upper eyelid. The eyelid is markedly

swollen, stiff and reddened in one spot. The eyelid is painful and causes

significant tearing of the entire eye. After examination of the eyelid, the

doctor concludes that it is a chalazion (eyelid cyst or Meibomian cyst). It is

an inflammation of the Meibomian gland of the eyelid, which can be seen in the

picture. What type of gland is it with regard to the mechanism of secretion?

View this question

The teacher wants to

demonstrate a typical serous gland to the students in practical exercises

focused on the glandular epithelium. However, he does not have much time to

think about it, because he has more tasks to complete. Which slide should he

choose to show the students typical serous acini?

View this question

A 19-year-old student

comes to the eye clinic with a very common problem today. He suffers from

cutting and burning eyes, the feeling of a foreign body in the eye, pressure,

and the feeling of tired eyes. The eyes are red. He is diagnosed with dry eye

syndrome. This can have many causes, and one of them is low tear production,

for example, as a result of taking certain medications. Tears are produced by

the lacrimal gland. The lacrimal gland is an exocrine gland. Its cells have a

basophilic cytoplasm and a round nucleus located in the basal third of the

cell. The basal part of the cells shows significant basophilia due to the

accumulation of polyribosomes and granular endoplasmic reticulum for the

production of proteins that are part of the produced secretion. The cells

contain zymogen granules, which are mostly released in a merocrine manner. What

type of gland is a lacrimal gland?

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A 54-year-old man underwent gastroscopy

(endoscopy of the upper digestive tract) for non-specific digestive disorders.

The oesophagus and stomach appear macroscopically fine, but changes are only

visible in the duodenum, where several samples are therefore taken for

histological examination. The final diagnosis is peptic duodenitis,

inflammation of the duodenum, which is a precursor to the development of the

ulcer. This inflammation is usually caused by the

Helicobacter pylori infection

in the stomach and

increased production of HCl in the stomach, which is also increased in the

duodenum. Among the features that can be observed histologically in this

inflammation is hyperplasia (enlargement) of the Brunner's glands of the

duodenum. What type of gland is this?

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A 4-year-old boy has recently returned from a holiday abroad and has now arrived now at the Clinic of Infectious Diseases with his parents due to severe

dehydration caused by diarrhoea. The causative bacterium is

Salmonella

,

which disrupts the structure of one type of intercellular junctions – tight

junction = zonula occludens. This physiologically prevents the passage of fluid

between cells – the so-called paracellular route. Disruption of these tight

junctions results in fluid loss into the lumen of the gastrointestinal tract.

Where can we find these tight junctions on cells?

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The student is asked about the difference

between the basement membrane and the basal lamina during the histology exam.

Until now, he thought that the two terms were identical. Could you advise him

what the difference is between these two structures?

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A newborn is

diagnosed with congenital deafness due to a defect in an intracellular protein.

This protein is a component of cell-cell junctions that form a pore connecting

the cytoplasm of adjacent cells. Which type of cell-cell junctions is defective in this patient?

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The teacher wants to

demonstrate a typical serous gland to the students in practical exercises

focused on the glandular epithelium. However, he does not have much time to

think about it, because he has more tasks to complete. Which slide should he

choose to show the students typical serous acini?

View this question

A 30-year-old patient underwent a biopsy of the

submandibular salivary gland in the ENT department due to significant swelling

of unclear origin. This eventually proves to be histologically normal. What is

this sample most likely to look like?

View this question

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