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YEAR-1 Course management

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A 10-year old boy has muscle weakness. Genetic testing reveals a mutation in Carnitine acyl transferase II (CAT II) gene and he is diagnosed with CAT II deficiency. Which single product arises from the reaction catalyzed by this enzyme?

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Mr. Ahmed has a peptic ulcer. His physician prescribes a drug that inhibits gastric acid secretion by blocking H2-recpetors. Which of the following drug is most likely prescribed?

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A 2 days-old male infant is born with herniation of intestine into umbilicus. Prenatal ultrasound scans during the pregnancy showed an abnormality of the anterior abdominal wall, which was suspected to be an omphalocele. At which week of development does failure of return of the intestinal lobe typically occur in this baby?

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A 57 year old man is brought to the ED with difficult swallowing. Imaging reveals injury of the swallowing afferent nerve fibers.

Which cranial nerve is most likely injured?

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A patient with severe hypertension is being treated with furosemide. What is the mechanism of action of this drug?

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A 48-year-old man is admitted to the hospital with severe abdominal pain. Radiographic examination reveals a tumor in the tail of the pancreas. A diagnostic arteriogram shows that the tumor has compromised the blood supply to another organ. Which organ is most likely to have its blood supply compromised by this tumor?

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A 55 year old woman with chronic kidney disease (CKD) visits the primary health care with progressive fatigue and pallor, investigations show normocytic normochromic anemia.

Which is the most likely kidney-related mechanism that best explains her condition?

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TCA cycle is also known as the amphibolic pathway (functions both in oxidative and synthetic processes). Which is the most likely enzyme that catalyzes co-reduction of FAD to FADH2 in this cycle?

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Water soluble vitamins have an important metabolic role in the human body.

What best describes water-soluble vitamins?

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A 32-year-old male patient arrives unconscious at the emergency department. The physician orders a blood sugar test, HbA1c and other laboratory investigations. Which is the most likely level of HbA1c in his condition?

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