Structure function relationship

The
image illustrates the structure and function of aquaporins, membrane proteins
that facilitate water transport across cell membranes. On the left, a
simplified representation depicts water molecules passing through an aquaporin
channel. On the right, a detailed view shows the aquaporin structure: the top
part displays the linear polypeptide with NPA motifs
(asparagine-proline-alanine), while the bottom part presents the folded,
functional form. Choose the correct answers:

Question

Structure function relationship

The
image illustrates the structure and function of aquaporins, membrane proteins
that facilitate water transport across cell membranes. On the left, a
simplified representation depicts water molecules passing through an aquaporin
channel. On the right, a detailed view shows the aquaporin structure: the top
part displays the linear polypeptide with NPA motifs
(asparagine-proline-alanine), while the bottom part presents the folded,
functional form. Choose the correct answers:

Answer

The central pore of the aquaporin tetramer
acts as a size-exclusion filter, allowing only small molecules like water to
pass.

Answer

Aquaporins
are arranged as tetramers, but each monomer acts as a water channel.

Answer

The tetrameric assembly of aquaporins is
essential for their function, as all four monomers together create a single
central pore, which is where the water transport happens.

Answer

The NPA
(Asn-Pro-Ala) motifs in aquaporins are located at the centre of the channel
relative to the cell membrane, suggesting they play a crucial role in water
selectivity.

Crowdly

Structure function relationship The image illustrates the structure and func...

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