The activity of drug candidates targeting CFTR has been presented as EC 50 . What is the difference between EC 50 and Kd?

Question

The activity of drug candidates targeting CFTR has been presented as EC 50 . What is the difference between EC 50  and Kd?

Answer

EC 50  is the concentration required to produce 50% of the maximum effect of the drug, whereas Kd is the concentration required to occupy 50% of the binding sites on CFTR

Answer

Kd and EC 50  both measure the concentration required to occupy 50% of the binding sites on CFTR, but each measure it in a different way

Answer

Kd is the concentration required to produce 50% of the maximum effect of the drug, whereas EC 50  is the concentration required to occupy 50% of the binding sites on CFTR

Answer

Kd and EC 50  both measure the concentration required to produce 50% of the maximum effect of the drug, but each measure it in a different way

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The activity of drug candidates targeting CFTR has been presented as EC 50 . Wha...

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