Tricyclic anti-depressants can be associated with abnormalities in cardiac function.
This is MOST LIKELY because these drugs:

Question

Tricyclic anti-depressants can be associated with abnormalities in cardiac function.  
 This is MOST LIKELY because these drugs:

Accepted Answer

simultaneously antagonise muscarinic receptors, while increasing noradrenaline levels.

Answer

displace noradrenaline from storage vesicles, leading to increased sympathomimetic effects.

Answer

block the metabolism of tyramine, leading to tachycardia.

Answer

antagonise pre-synaptic alpha2 receptors, leading to enhanced sympathomimetic effects.

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