Q12. Nucleotide sequence similarity searches reveal that the blue genes in the pathogenicity island likely encode a unique fimbrial adhesin and the proteins required to assemble this adhesin. Many uropathogenic E. coli (UPEC) strains encode two types of fimbrial adhesins (Pap and type 1 pili). In what way does this impact the virulence of UPEC?

Question

Q12.  Nucleotide sequence similarity searches reveal that the blue genes in the pathogenicity island likely encode a unique fimbrial adhesin and the proteins required to assemble this adhesin. Many uropathogenic  E. coli  (UPEC) strains encode two types of fimbrial adhesins (Pap and type 1 pili). In what way does this impact the virulence of UPEC?

Answer

Expressing both fimbrial adhesins expands the tissue tropism of UPEC.

Answer

The fimbrial adhesins work together to facilitate motility during infection.

Answer

Expression of both fimbrial adhesins is required to cause an infection.

Answer

The fimbrial adhesins both adhere to proteins on the UPEC cell surface allowing microcolony formation during infection.

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Q12. Nucleotide sequence similarity searches reveal that the blue genes in the...

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