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The phage kills the bacteria by hijacking it's transcription and translational machineries.
The research identifies a specific bacterial gene sequence that normally gets transcribed and translated into a short peptide. After phage infection, they discover a phage-derived sequence replacing this bacterial sequence, leading to a different amino acid sequence.
Bacterial DNA sequence - 5'- GTG ATG TTT GGC AAC TGA TAA-3'
Phage DNA sequence - 5' - GTG ATG TTC TGA GGA AGC TAA -3'
(i) Determine the correct bacterial and phage mRNA sequence. (1.5 marks)
(ii) Determine the correct bacterial and phage polypeptide sequence. (1.5 marks)
(iii) Explain 2 specific ways in which altering the poylpeptide sequence can help disrupt the bacterial cell functioning (1 mark).
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