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What would be the reason for choosing to treat an infection with both avibactam and amoxycillin?
Avibactam is a suicide inhibitor of β-lactamase enzymes, so it saves the amoxycillin, which is a suicide inhibitor of penicillin binding proteins
Amoxycillin is a suicide inhibitor of β-lactamase enzymes, so it saves the avibactam which is a suicide inhibitor of penicillin binding protein
Both of these compounds are β-lactams and inhibit penicillin binding proteins, but by binding at different sites, so they act synergistically
Amoxycillin is a β-lactam antibiotic while avibactam is a protein synthesis inhibitor, so they act synergistically
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