Microarrays provide a genome-wide view of expression, while RNA sequencing is limited to specific gene

Microarrays are less effective at quantifying transcripts with small differences in expression compared to RNA sequencing.

Microarrays cannot detect novel transcripts or splice variants, as they rely on predefined probes

Microarrays have a limited dynamic range for measuring gene expression, leading to saturation at high transcript levels.

Microarrays have a higher sensitivity for low-abundance transcripts compared to RNA sequencing