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Individuals with Gorlin Syndrome are:

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Individuals with Gorlin Syndrome are:

highly sensitive to UV-light induced DNA damage due to gain of function mutations

0%

at an increased risk of basal cell carcinoma due to loss of function mutations in the PTCH gene

100%✨

at an increased risk of basal cell carcinoma due to gain of function mutations in the PTCH gene

0%

at an increased risk of basal cell carcinoma due to reduced Hedgehog signalling

0%

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