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Which of the following BEST describes the mechanism(s) underlying the activation...

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Which of the following BEST describes the mechanism(s) underlying the activation of wild-type B-RAF?

B-RAF binding to Ras-GTP, and its heterodimerisation with SOS

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B-RAF binding to Ras-GTP, and homo-dimerisation via its kinase domain

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B-RAF binding to Ras-GDP, and its phosphorylation by SOS

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B-RAF binding to Ras-GTP, and its phosphorylation by Ras

❌

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