For a patient who was found to have the ∆508 deletion in their CFTR gene, why should the patient take both lumacaftor and ivacaftor?

Question

Answer

Lumacaftor assists in ensuring more of the mutant CFTR protein is properly assembled in the membrane, whereas ivacaftor promotes opening of the CFTR chloride ion channel

Answer

Lumacaftor corrects the folding of the mutant CFTR protein, after its assembled in the membrane, whereas ivacaftor promotes the opening of the CFTR chloride ion channel

Answer

Ivacaftor assists in ensuring more of the mutant CFTR protein is properly assembled in the membrane, whereas Lumacaftor promotes opening of the CFTR chloride ion channel

Answer

Opening of the CFTR chloride ion channel is promoted by both drugs

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For a patient who was found to have the ∆508 deletion in their CFTR gene, why sh...

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