Trigeminal peripheral branches innervate the meninges of the infratentorial compartment

The main nucleus is in the tegmentum of the rostral pons

The spinal nucleus receives information also from peripheral territories innervated by the IX and X cranial nerve

Third order sensory neurons are in the VentroPosteroMedial (VPM) nucleus of the thalamus

The mesencephalic nucleus projects directly to the thalamus

Information coming from cerebral and meningeal vessels are relayed to the spinal trigeminal nucleus