Hereditary mutation in the Rb gene is characterised by the passing of the defective gene to newborns in an autosomal recessive manner

Loss of the Rb gene function is characterised by an inability to regulate cell cycle checkpoints, potentially leading to urinary bladder tumour formation

Retinoblastoma is characterised by a mutation in a copy of of the Rb gene, resulting in a loss of the gene's function

Hereditary mutation in the Rb gene is charaterised by all cells containing a defect on chromosome 14

Rapidly dividing somatic cells

Slowly dividing somatic cells

Brain cells

Nerve cells

Natural killer cells

Oncogenes

Proto-oncogenes

Angiogenesis

inner cell mass and trophoblast

blastoderm and mesoderm

epiblast and hypoblast

ectoderm, mesoderm and endoderm

They are committed

They are specified

They are not differentiated

They are not determined