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A particular genetic event that will occur with a low probability can affect the answer to Q10c, (i) what is it? (ii) explain how this event occurs.
In other mapping studies it has been determined that the PKD gene is 10 map units from each of the closest flanking markers. If individual II-7 decided to have a child (the other biological parent is unaffected), and an amniocentesis showed he had transmitted allele A2 to the unborn child, what is the probability that the child has inherited the disease allele?
Give your answer as a decimal number, not a fraction or percentage. One decimal place only please.
Inequality in genetics and genomics is an important global issue. For example we need global genomic representation to accurately predict who will develop diseases. At the current moment, the majority of association studies have used European ancestry population datasets. This issue is evident in the results below, when we compared polygenic risk scores for type 2 diabetes of the same individual but testing against two different ancestries.
By using the data from which ancestry would have communicated the lower risk of developing type 2 diabetes?