QInB=43

A patient with myasthenia gravis is treated with pyridostigmine (60 mg orally every six hours). Pyridostigmine has an oral bioavailability of approximately 75% and a half-life ranging from 3–4 hours.
What is the primary mechanism by which pyridostigmine improves muscle strength?

Question

QInB=43
 
 A patient with myasthenia gravis is treated with pyridostigmine (60 mg orally every six hours). Pyridostigmine has an oral bioavailability of approximately 75% and a half-life ranging from 3–4 hours. 
  What is the primary mechanism by which pyridostigmine improves muscle strength?

Answer

Direct stimulation of nicotinic receptors at neuromuscular junctions

Answer

Activation of adrenergic beta-2 receptors improving skeletal muscle contraction

Answer

Blockade of muscarinic receptors reducing parasympathetic tone

Answer

Competitive antagonism at histaminergic H1 receptors

Answer

Reversible inhibition of acetylcholinesterase increasing acetylcholine levels at neuromuscular junctions

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QInB=43 A patient with myasthenia gravis is treated with pyridostigmine (60 m...

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