is a process whose selectivity depends on the state of the pedicels of the visceral layer of Bowman's capsule

is increased when the sodium load on the macula densa is high (tubulo-glomerular feedback )

is the asymptotic value for renal clearance for any substance at very high concentrations

is a process strongly influenced by blood pressure

is a selective process by which unneeded and toxic substances are eliminated

is a process whose magnitude depends on the state of the pedicels of the podocytes

changes more than reabsorption in response to changes in blood pressure (pressure induced natriuresis)

is an unspecific process that involves all sufficiently small molecules

is a process of passive diffusion

is reduced by aldosterone

is the most important process in the elimination of lipophilic substances

pressure-induced natriuresis

a long-term positive feedback on GFR (increased) and negative feedback on blood pressure (lowered)

hyperpolarization of the macula cells and depression of the RAAS system

swelling of macula cells, release of ATP and decrease in GFR by indirect constriction of the afferent arteriole

a rapid (<1 min) negative feedback on GFR (tubulo-glomerular feedback)

depolarisation of the macula cells, release of prostaglandins and activation of the RAAS system

swelling of macula cells, release of ATP and increased diuresis by preferential contraction of the efferent arteriole