IMM2011 - Basic immunology: The body's defence system - S1 2025
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How many unique epitopes can an individual IgM antibody recognise
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How many antigen binding sites does an IgM antibody have?
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A thymocyte is undergoing development and is at the stage of generating its antigen receptor. In the event that it does not initially generate a successful TCR beta chain, what will occur?
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Which form of recombination provides the most diversity in an antigen receptor?
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2. Using any information gained today, translate the following nucleotide sequences and indicate if they could generate a functional TCR. TCR beta chain: TTGCACTTTGGAGCGGGCAAGATATCTTTAAGGAAACAAACGCGC TCR alpha chain: GATCCTTATGACCGAGCTCAGGTCCAACTCCAATTCCACGGACTTAGT
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In the generation of one antigen binding site of a TCR, how many CDRs are involved?
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Comparing B and T cells, which of the following statements is TRUE?
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The major variations that are found between the different MHC class II molecules within a population will be:
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Inflammasome activation requires caspase-1 to:
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Name these cells in order from left to right (1 to 4):
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