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BCH2011 - Structure and function of cellular biomolecules - S1 2025

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Shown below are three short DNA duplexes.

What is the correct order of stability of these duplexes (from most stable to least stable)

[Note: You do not need to calculate Tm values. You should be able to determine the order of stability “by eye”.]

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The image below is a helical wheel representation of part of an alpha helix (top-down view), with each amino acid a numbered circle.

Without knowledge of any R groups, non-covalent interactions between which ONE of the following pairs of amino acids will likely help stabilise the helix?

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How many peptide bonds are there in the following peptide sequence?

MetCysGlySerProLeu

(Enter a number in digits with no additional characters)

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Why is glycine (shown below) the only non-chiral amino acid?

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A key characteristic of the alpha helix is:

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Fibrous proteins typically have a tertiary structure that:

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Quaternary structures:

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A protein structure was elucidated and found to contain a specific pattern of alpha helices and beta sheets previously observed in many different proteins. This is an example of: 

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The image below is a helical wheel representation of part of an alpha helix (top-down view), with each amino acid a numbered circle.

Without knowledge of any R groups, non-covalent interactions between which ONE of the following pairs of amino acids will likely help stabilise the helix?

Image failed to load

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How many peptide bonds are there in the following peptide sequence?

MPGA

(Enter a number in digits with no additional characters)

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