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BCH2011 - Structure and function of cellular biomolecules - S1 2025

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Compare the two DNA duplexes shown below.

Duplex 1                  Duplex 2

5′-TACGTGGAAG-3′          5′-AGATGGCGCG-3′

3′-ATGCACCTTC-5′          3′-TCTACCGCGC-5′

Which of the following statement(s) is/are correct?

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Which of the following statements correctly identifies a hydrogen bond donor and a hydrogen bond acceptor in the base pair structure shown below?

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Choose the best option to complete the following statement.

In the process of DNA synthesis, the problem of making the reaction energetically favourable is solved by:

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One strand of a DNA duplex has the sequence:

5′-CACAGAACGC-3′

Type the sequence of the complementary strand in the 5′ to 3′ direction.

Be careful not to type any spaces or additional characters. For example, if you think the answer is 5'-AGCC-3', simply type AGCC.

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Tertiary structure can be defined as:

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What arises as a consequence of structural diversity in globular proteins?

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Secondary structures predominantly arise due to:

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How many peptide bonds are there in the following peptide sequence?

AVFHHEW

(Enter a number in digits with no additional characters)

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The image below is a helical wheel representation of part of an alpha helix (top-down view), with each amino acid a numbered circle.

Without knowledge of any R groups, non-covalent interactions between which ONE of the following pairs of amino acids will likely help stabilise the helix?

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Ribosomes are a supramolecular complex of ribosomal RNA and multiple protein subunits. This therefore represents an example of:

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