Q14. What administration / delivery method would be most compatible with the KVD mRNA vaccine?

Q10. What is the herd immunity threshold required to prevent transmission of KVD?

Q11. The research team considers developing a recombinant antigen vaccine or a DNA vaccine. Which statement is true for these vaccine types?

Q8. The therapeutic administration of cytokines via subcutaneous injection is associated with improved clinical outcomes for patients with Kipu Virus Disease (KVD). Which of the following cytokines would you recommend as a therapeutic for KVD?

Q6. Natural Killer (NK) cells can induce apoptosis in kipu infected cells. The activation of NK cells is dependent on two distinct types of cell surface receptors – activating and inhibitory. Select the correct statement:

Q9. Cytokine therapy is typically administered in combination with another antimicrobial agent. Which of the following antimicrobial agents would you prescribe to treat a kipu virus infection?

Q7. High affinity neutralising antibodies:

Q5. The immunologist examined the subcellular localisation of MHC-I in intestinal epithelial cells (IECs) that were cultured with the kipu virus (infected IECs) or a mock virus (control IECs). The results are summarised in the graphs below. What effect does kipu virus infection have on MHC-I processing and presentation in IECs? How would this impact the adaptive cell-mediated immune response in a kipu infected patient? (2-3 sentences) (2 marks)

Q4. Which class (or classes) of Pattern Recognition Receptor (PRR) will detect the viral double-stranded RNA genome in the cellular cytoplasm? (select all that apply)

Q26. Describe two public health interventions that could be implemented in Minton to break the H. mentis chain of infection and reduce the prevalence of aqualunosis. (2 sentences) (2 marks)