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DEV3011 - Experimental developmental biology and disease modelling - S1 2026

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Where would you expect TGFB-3 to be expressed in the chicken embryo facial region?

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Cleft palate can be caused by either genetic or environmental factors.

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The image below is a ventral view of the craniofacial region in a human embryo.

What does X point to?

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Cranial neural crest cells are pre-patterned before they migrate.

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DLX genes regulate the anterior-posterior patterning of the branchial arches

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A zebrafish embryo has as loss-of-function mutation in genes early in the Hoxa and Hoxd series  (Hox1-4). What would be the result in the developing craniofacial area?

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What does branchial arch # 1 give rise to?

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Treacher-Collins

syndrome features hypoplasia of facial bones

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A mouse embryo has a loss-of-function mutant in Sox10, which has impeded proper cranial neural crest migration. What would be the most likely result?

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Which of the following below is an example of polyphenism?
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