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DEV3011 - Experimental developmental biology and disease modelling - S1 2026
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What is the significance of cortical rotation in the frog embryo?
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You plan to insert a gene into the genome of zebrafish embryos, using CRISPR/Cas9. What would NOT typically be involved in your approach?
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What organising centre in the Xenopus embryo is the functional equivalent of Hensen’s node in chick?
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Inducible knockout mouse models permit temporal control over the induction of specific gene knockouts. Tamoxifen is commonly used to induce Cre-mediated recombination in mouse models. How does tamoxifen act?
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What is the result of the FLP-FRT system used in Drosophila?
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Epidermal growth factor secreted by a cell can bind to its receptor on that cell. This is an example of what developmental process?
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You seek novel genes involved in apoptosis in C. elegans. What technique would you use?
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What is the function of the C. elegans ced-9 protein?
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What happens to FGFR's when FGF's bind?
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Isolated cells from the dorsal part of a frog embryo can form back cells if isolated and grown in culture and when transplanted into the belly region, they form back cells. This is an example of what developmental phenomenon?
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