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DEV3011 - Experimental developmental biology and disease modelling - S1 2026
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A researcher plans to use CRISPR/Cas9 for non-homologous end joining (NHEJ) in the mouse embryo. What is NOT part of the method?
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A student has used DAPI staining to observe a C. elegans specimen. What does DAPI stain?
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In cells of the dorsal neural tube, Smad2 has become phosphorylated. What does this mean?
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Which cell type below has the lowest degree of potency?
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A researcher wants to study the development of endothelial cells, and decides to make a transgenic zebrafish to visualise endothelial cells using time-lapse imaging as they develop. What does the researcher need to make such a transgenic?
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What method could you use to detect where in the embryonic mouse neural tube the enzyme lactate dehydrogense is located?
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Consider the image below of an E6.5 mouse embryo.
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A PhD student has conducted the ENU screen in mice and has observed a phenotype in the G1 as shown below.
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In the image below of the CRISPR/Cas9 system, what does the black arrow denote?
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The image below shows DAPI staining. What is is staining?
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